Deicide first began in Tampa, Florida in July of 1987. They are influenced by bands such as Destruction, Sodom, Venom, Bathory, Possessed, Death and Slayer. Their first demo, Feasting the Beast, was an 8-track demo recorded in Benton's garage. In 1989, they recorded their second demo, Sacrificial, at Morrisound with producer Scott Burns. After tons of lineup changes, Benton assumed the additional role of vocals and the band was renamed Carnage.

Benton reportedly barged into Roadrunner Records' A&R man Monte Connors' office and presented him with the demo, saying, "Sign us!" The next day contracts were issued to the band. In 1989 the band's name was changed to Deicide at the request of Roadrunner Records. Deicide then released their self-titled debut album, also produced by Scott Burns at Morrisound, in 1990. Their debut featured re-recorded versions of all six of the Sacrificial tunes. This lineup remained intact until November 25, 2004.

Shortly after, the guitar roles were then filled by ex-Cannibal Corpse guitarist Jack Owen, and Vital Remains guitarist Dave Suzuki. Following the tour, Suzuki was replaced by Ralph Santolla, formerly of Death, Iced Earth and Sebastian Bach , Deicide's eighth studio album The Stench of Redemption received rave reviews, and is one of their biggest sellers. On May 24, 2007, it was announced Ralph Santolla had left Deicide to join Florida's Obituary. He appears on their album Xecutioner's Return. By November 2007 Deicide began to work on its ninth studio album at Morrisound Studios. Entitled Till Death Do Us Part, it promised to be Deicide's "most savage and aggressive offering to date." Deicide posted a blog on their official Myspace page saying they had signed a worldwide record deal with Century Media, with Ralph Santolla returning to the band for a European tour. They are now working on material for a summer 2010 release.

Guitarist Kevin Quirion of Order of Ennead joined the band in the summer of 2009. Kevin has a very unusual picking style, but it lends it self very well to speed metal. Check it out.